SILENCING OF PARP2 BLOCKS AUTOPHAGIC DEGRADATION

Silencing of PARP2 Blocks Autophagic Degradation

Poly(ADP-Ribose) polymerases (PARPs) are enzymes that metabolize NAD+.PARP1 and PARP10 were previously implicated in the Car Accessories regulation of autophagy.Here we showed that cytosolic electron-dense particles appear in the cytoplasm of C2C12 myoblasts in which PARP2 is silenced by shRNA.The cytosolic electron-dense bodies resemble autophagic

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Monitoring the Prevalence of Leucocytozoon sabrazesi in Southern China and Testing Tricyclic Compounds against Gametocytes.

Leucocytozoon parasites infect many species of avian hosts, including domestic chicken, and can inflict heavy economic loss on the poultry industry.Two major species of Leucocytozoon parasites have been reported in China, L.sabrazesi and L.caulleryi, although L.sabrazesi appears to be more widespread than L.caulleryi in southern China.The tradition

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Decompression Retinopathy after ExPRESS Shunt Implantation for Steroid-Induced Ocular Hypertension: A Case Report

Purpose.To present a unique case of decompression retinopathy after the implantation of ExPRESS drainage device.Method.A 25-year-old female patient underwent Car Accessories implantation of ExPRESS drainage device in the left eye for the management of steroid-induced ocular hypertension.Results.On the postoperative day one, best-corrected visual ac

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